Cancer and Biology Research Paper Example | Topics and Well Written Essays - 1000 words

Cancer and Biology - Research Paper Example The presence of cancer in the body leads to the damage of the body cells that undergo unrestrained division to form tumors. Consequently, tumors correspond to lumps of tissue. It is only in the case of leukemia that cancer does not allow division of the cell as the normal function of the blood. The growth of the tumors leads to the interference of circulatory, digestive and the nervous systems. Tumors also release hormones that change the functions of the body. However, not all tumors are dangerous in nature. Tumors that do not grow and move can be beneficial to the body (Ruddon, 2007). The dangers and malignancy of tumors occur in either of the two conditions. The initial condition is apparent when a cancerous cell uses the lymph system and blood to move throughout the body. As the cell moves, it destroys the healthy tissues of the body. This procedure is called invasion. The second condition is when the cancerous cell manages to undergo division and growth. As this happens, the cel l will make fresh blood vessels to feed itself in a process denoted as angiogenesis. Metastasization occurs when the tumor manages to extend to other body parts and grow. As a result, it will invade and destroy additional healthy tissues of the body. ... This can stop the growth tumors in the secondary states (Bozzone, 2007). Causes of cancer Cancer results from the uncontrollable growth cells that are not fatal. Ordinary cells follow the normal path of growth, division, and death. The demise of cells in a planned way is called apoptosis. The breaks down of this program lead to the formation of cancer. It is clear that cancer cells do not undergo programmed deaths as other regular cells. They instead keep up with growth and continue to grow. This culminates in the formation of a network of abnormal cells whose growth is out of control. However, most of the causes of cancer come from external interventions. The main causes of cancer are related with the environmental risk factors like radiations. When one exposes himself to radiations of high levels such as x-rays and therapies, the normal body cells are damaged. This increases the dangers of acquiring leukemia, breast cancer, thyroid cancer, and stomach cancer. Besides, the ultraviol et radiation that originates from the sun culminates in skin cancer that damages the melanoma. The harmful rays from the sun can cause early aging and skin damages (Bozzone, 2007). The other causes of cancer are viruses, chemicals, tobacco, alcohol, and poor diet. Viruses such as human papillomaviruses (HPV), Epstein Barr virus, hepatitis B and C are responsible for causing infectious mononucleosis that increases the risks of acquiring cancer. Additionally, diseases that affect the immune body system of the body such as AIDS make the body vulnerable to cancers. As such, chemicals such as asbestos, radon, nickel, uranium, pesticides, and the benzene also enhance the risks of acquiring

Should employers be allowed to ask for an employee's social networking Research Paper

Should employers be allowed to ask for an employee's social networking information Can an employee's Facebook or Twitter activity impact their job Is this fair Necessary - Research Paper Example â€Å"Traditional social networks have expanded from a few dozen acquaintances to hundreds of friends, friends of friends, connections and followers† (Kelleher, 2009). Employees’ use of social media websites is a matter of huge concern for some employers, while others are indifferent to the employees’ Facebook and Twitter activities. In either case, employers have very little control over their employees’ social media activities. Employers cannot deny the employees’ right to use these websites. This paper explores this matter from numerous dimensions. Social media websites are places of casual chit chat. They are forums where juniors can interact with their seniors in a comparatively casual way. Sometimes, managers and leaders have a rosy view about letting their subordinates the freedom to ask them personal questions or interact with them on an equal level. When a manager gets a friend request from an employee, he/she may not want to accept that, yet he/she half-heartedly accepts the request just to keep his relationship with him/her good. Some employees tend to have separate work and social identities and yet there are others who don’t differentiate between the two. This lack of dual identity is not always appreciated by others. Many people are very particular about not discussing business issues outside the workplace. When a subordinate or manager does discuss them on Facebook or Twitter, this may be very irritating for the other person. Many employees have been fired in the past for discussing their job related issues on the Facebook and Twitter. â€Å"Five workers fired for complaining about their jobs on Facebook will go back to work after the National Labor Relations Board ruled in their favor, affirming workers can safely vent their frustrations about the workplace on social networks† (Forbes, 2011). This raises challenges for the governing bodies that have to take a lot of criticism both if they decide in favor of the employees or

Genetic Mapping of Cystic Fibrosis and Huntingtons Disease

Genetic Mapping of Cystic Fibrosis and Huntingtons Disease Genetic Mapping By the late 1970s, the list of genetic diseases in McKusicks catalog of genetic diseases had grown exponentially. But only a few of the actual genes were identified, leading to predictive diagnostic tests. It seems that finding a disease-linked gene in humans is like looking for a needle in a haystack. Botstein/Davis Gene Mapping Technique In 1978, David Botstein (1942- ), a geneticist from MIT, attended a genetic mapping presentation in Utah. At the presentation, a graduate student was mapping a gene that happened to be sitting with a gene that existed in many easily identifiable variants. As Botstein listened, he was struck by an idea: gene mapping would become a trivial task if such variant signposts existed and were spread across the human genome. Botstein knew that such a marker exists. Over centuries of evolution, thousands of minute variants in DNA sequence are created in the human genome. These variants are called polymorphisms, and are spread widely over the human genome. Working with Ron Davis (1941- ) and Mark Skolnick (1946- ), Botstein published their new basis for the construction of human genetic maps in 1980. Mapping Huntingtons Disease (HD) Nancy Wesler, a psychologist, heard about Botsteins gene-mapping proposal in October, 1979.ÂÂ   Her mother and uncles all had suffered from Huntingtons disease, but she was still asymptomatic. Huntingtons disease causes the death of specific neurons in the brain, leading to jerky movements, physical rigidity, and dementia. Symptoms usually appear in midlife and worsen progressively. At that time, Botsteins method was still theoretical thus far, no human gene had been successfully mapped with it. Botsteins technique was crucially dependent on the association between a disease and markers: the more patients, the stronger the association, the more refined the genetic map. There were only a few thousand HD patients in scattered across the United States seemed perfectly mismatched to this gene-mapping technique. However, Wexler had heard that there was a prevalence of HD on the shores of two villages in Venezuela. In the winter of 1979, Wexler set off to Venezuela to hunt the Huntington gene. She hired a team of local workers to begin documenting the pedigrees of affect and unaffected men and women, collecting blood samples to be shipped to the laboratory of James Gusella, at the Massachusetts General Hospital in Boston, and to Michael Conneally, a medical geneticist at Indiana University. In Boston, Gusella purified DNA from blood cells and cut it with a barrage of enzymes, looking for a variant that might be genetically linked to HD. Conneallys group analyzed the data to quantify the statistical link between the DNA variant and the disease. In 1983, three years after the blood samples had arrived, the location of the HD gene, whose mutation causes Huntingtons disease, was mapped to chromosome 4 in 1983, making HD the first disease gene to be mapped using DNA polymorphisms variants in the DNA sequence. The mutation consists of increasing repetitions of CAG in the DNA that codes for the protein huntingtin. The number of CAG repeats may increase when passed from parent to child, leading to earlier HD onset in each generation. Mapping of Cystic Fibrosis (CF) Davis and Botsteins technique of mapping genes based on their physical positions on chromosomes later called positional cloning marked a transformative moment in human genetics. In 1989, the technique was used to identify a gene that causes cystic fibrosis, a devastating illness that affects the lungs, pancreas, bile ducst, and intestines. Unlike Huntingtons disease, the mutated variant of the CF is common: one in twenty-five men and women of European descent carries the mutation. Human with a single copy of the mutant gene are largely asymptomatic. If two such asymptomatic carriers conceive a child, chances are one I four that the child will be born with both mutant genes. Until the 1980s, the average life span of a child carrying two such mutant alleles was twenty years. In 1985, Lap-Chee Tsui, a human geneticist working in Toronto, found an anonymous marker that was linked to the mutant CF gene. The marker was quickly pinpointed on chromosome seven, but the CF gene was lost somewhere in that chromosome. Tsui began to hunt for the CF gene by progressively narrowing the region that might contain it. In 1989, using a modified gene hunting technique called chromosome jumping, Tsui and his colleagues had narrowed down the gene hunt to a few candidates on chromosome seven. The task was now to sequence the genes, confirm their identity and define the mutation that affect the function of the CF gene. They discovered that only one gene was persistently mutated in both copies in affected children, while their unaffected parents carried a single copy of the mutation. The CF gene codes a molecule that channels salt across celluar membranes. The most common mutation is a deletion of three bases of DNA that results in the removal, or deletion, of just one amino acid from the protein. This deletion creates a dysfunctional protein that is unable to move chloride across membranes. The salt in sweat cannot be absorbed back into the body, resulting in the characteristically salty sweat. Not an the body secrete salt and water into the intestines, resulting in the abdominal symptoms. Within a few months of the discovery, a diagnostic test for the mutant allele became available. Over the last decade, the combination of targeted parental screening and fetal diagnosis has reduced the prevalence of children born with CF by about 30 to 40 percent in populations where the frequency of the mutant is the highest.

Animal Farm - Knowledge Is Power Essay -- essays research papers

George Orwell’s novel ‘Animal Farm’ is an allegorical fable of the Russian Revolution. It depicts the Revolution in a way that is inoffensive to people and also very easy to understand. This controversial novel also teaches many valuable lessons, all very true in man’s past and also in the present. In all of man’s histories, there are legends of tyrannical kings and merciless emperors, corrupted with the thirst for ultimate power. Education also played an important role in the subjugation of mankind; the intelligent and educated use their knowledge to undermine and control the naà ¯ve uneducated proletariats. The naà ¯vetà © of an ignorant working class is detrimental to any society; neither communist nor democratic societies are unaffected. Power is a blessing and also a curse, cast upon man and affecting us all, nevertheless, it affects those without power, as well as those with power. All great leaders had and have great power. Power is not biased, it does not make a good leader a good person, but it can make a good person a tyrannical and merciless leader. For example, Adolf Hitler was a great leader, but he was a very bad man. Due to the knowledge, cunning and coaxing of education, leaders can become corrupted and tainted, tainted with the poison of corruption laced in their meal of power and control. Such was what occurred in ‘Animal Farm’; the pigs who were educated gained power and control over Manor Farm, which under the concept of Animalism, they called Animal Farm. Fro...

Legoland’s main target market is families with young children

The families would enjoy a great day out while having fun with there children. The young children will have lots to do as the park is really based around them. Legoland has over 50 fantastic rides and attractions. Families with older children would not prefer Legoland, as they would not gave a fun day compared to, if they went to Thorpe Park. Thorpe Park is a thrill park and would excite them a lot more then Legoland. This is mainly because this is not the age group Legoland has targeted. Only one or two rides would attract the older children compared to nearly all the rides at Thorpe Park. Thorpe Park mainly attracts people from the age of 12 upwards as it is a thrill-seeking park. Young couples again would not have such a great time here purely because the park does not appeal to them. However they can enjoy some rides and have photos as most rides have ride photography. But Thorpe Park would be a better option, as they would enjoy themselves a lot more, with better thrill seeking rides. Legoland's nearest competitor would have to be Thorpe Park but they are two totally different parks as Legoland is aimed at 3-12 year olds where as Thorpe Parks target market is teenagers and adults. Thorpe Park is basically a thrill park as all the rides are quite intense. Some of the intense rides are the Colossus, Nemesis Inferno, Quantum, Detonator and Rumba rapids. The prices between Thorpe Park and Legoland are quite similar but a 14 year old for example would much prefer spend there money at Thorpe Park as it is better value for money for over 12's. Thorpe Park Legoland Adults- à ¯Ã‚ ¿Ã‚ ½26.00 Adults- à ¯Ã‚ ¿Ã‚ ½22.95 Children- à ¯Ã‚ ¿Ã‚ ½19.50 Children- à ¯Ã‚ ¿Ã‚ ½19.95 Seniors- à ¯Ã‚ ¿Ã‚ ½17.00 Seniors- à ¯Ã‚ ¿Ã‚ ½16.95 Legoland is a unique park because it is the only park that offers something for younger children in the Royal Borough and is probably the best known in the UK. The closest family park to Legoland is Beavers Park inside the Pleasure Beach at Blackpool and also Paulton Park in New Forest. Paulton's Park is situated in a beautiful parkland setting of 140 acres with colourful gardens, sweeping lawns and a horseshoe shaped lake. It is a place full of fun, action and excitement. There are a variety of things to see and do for all ages. There are 40 different rides and attractions, fast and slow, wet and dry. Some of the features on offer are the Family Roller Coaster, Raging River Ride, Tiny Tots Town, Kids Kingdom, Clock Maze and there are many more. There are not a lot of comparisons between Legoland and Paulton Park. Paulton Park has fewer rides then Legoland though, but only by a few. Paulton Park is not advertised as much as Legoland and Paulton Park is not well known as Legoland in the UK. Legoland has also a better catchment area then Paulton Park. Legoland is very close to London, the capital of England also only 12 miles away from Heathrow airport. Also Legoland has many attractions nearby as it is situated in Windsor, which is a very popular tourist attraction. Paulton Parks catchment area is Bournemouth, Southampton and Brighton. Poulton Park is not commercialised enough. There are not a lot of improvements needed for Legoland as it is a very successful company and appeals to there target market very well. They are probably the best family park in the UK. To increase visitor figures they could build a couple more rides that would attract more teenagers. Maybe a thrill ride, this will attract a much wider range of people to Legoland. They could also make more rides to expand the park and make their customers day longer and more special. NEW FOREST LOCATION The New Forest is situated in the Southern part of England. A superb family holiday destination, flanked by the sea-faring cities of Portsmouth, Southampton and the town of Poole. New Forest extends to the South coast and the Isle of Wight. The New Forest has 93,000 acres of woodland and open-land brimming with wildlife. It is the largest un-enclosed area in Southern England, with ponies, donkeys, cattle, pigs, deer's and more roaming freely. There are a lot of activities that you can take up when you're at New Forest; the activities include horse riding, camping, walking, cycling and water sports. New Forest was set aside as a special place over nine centuries ago by William the conqueror. When you enter New Forest today, it appears that you're going backwards in time. The landscape is unique and traditions exist here that are unchanged since medieval times. New Forest is well known as an Area of Outstanding Natural Beauty (AONB). The catchment area for New Forest is quite good with a few major towns and cities nearby. Major towns and cities within two hours of New Forest are Bournemouth, Southampton, Brighton, Windsor, Bristol, Dover and London. The District has a resident population of 171,000, distributed between six main centres and many small villages. As in most rural communities there is considerable concern to maintain the unique quality of life, including not only the attractiveness of the area but also local services. Populations: Bournemouth- 163,444 One-Hour Drive of New Forest Southampton- 217,445 Brighton- 247,817 One and a Half Hour Drive of New Forest Bristol- 380,615 Windsor- 133,626 Two-Hour Drive of New Forest London- 7,172,091 Dover- 104, 566 Visitor Breakdown Millions enjoy the New Forest each year. The majority of visits are by local people within the district, this is approximately 10 million a year by the locals. A further 3.5 million are day visits from further afield and 2.5 million are visits by people staying overnight in the area. They come primarily for fresh air, recreation and peace and quiet. The New Forest also has many features and attractions for visitors. I think New Forest is suited to every age group. Some of the top attractions include Paulton's Park, Art sway, New Forest Cider Farm, Setley Ridge Vineyard, Cal Shot Castle and possibly one of the most popular reasons for visiting New Forest is the beautiful wildlife. Paulton Park is a place full of fun, action and excitement. Children would just love it here, with lots to do. It is very similar to that of Legoland in Windsor. There are 40 different rides and attractions, fast and slow, wet and dry. Some of the features on offer are the Family Roller Coaster, Raging River Ride, Tiny Tots Town, Kids Kingdom, Clock Maze and there are many more. Art Sway attracts many visitors who are interested in the modern day art designs and paintings. New Forest Cider Farm and Setley Ridge Vineyard are the ideal places to buy and experience how and where wine is grown, produced and bottled. The main target here is at the adults, it gives them a chance to buy and taste freshly brewed alcohol. Whilst on your visit to New Forest there is a great chance to visit one of Henry VIII's monuments, the Cal Shot Castle. Visitors have the chance to get right up close with the animals, as there are wild ponies and goats roaming free in the wild. The forest offers a number of centres with different animals on show, with Europe's largest gathering of multi-specied otters and owls. There are two beautiful sites you can visit they are Wildlife Park and also Longdown Activity Farm. There are a lot of activities that you can take up when you're at New Forest; the activities include horse riding, camping, walking, cycling and water sports. ACCESS Visitors can come to New Forest by car, rail and sea. By Road The road links for New Forest are excellent with the M3 and M27 providing access from London and the South East. If you are travelling from the Midlands you have the benefit of the M40 and A34. By Rail You can get to the New Forest from all over the country by train. There are over 130 stopping trains a day at Brockenhurst, which is on the mainline from London Waterloo, this is a one and a half hour journey. By sea Wightlink Ferries operate frequent services from the Isle of Wight to Lymington. P&O European Ferries operate services from Le Havre, Cherbourg and Bilbao. Brittany Ferries run services from Caen, St Malo and Santander. By Air The major London airports, Gatwick and Heathrow, are less than 100 miles away. Just outside New Forest there are Southampton and Bournemouth International Airports. These are easily accessible via good rail and coach connections.

How I Spent My Holiday

How you spent your last holiday During my last school holidays, I spent a few days at my cousin’s house at Morib, a well-known sea resort. I shall never forget that visit. On the day I arrived at Morib, my cousin told me that he would do to make my stay there a very interesting one. He said that he would make a raft to use it in the sea. Then he would buy fishing net to catch some fish in the shallow water near the coast. When I heard all this, I was very delighted because it was one of the reasons that I had decided to visit my cousin.We then walked up to the beach which is near his house. While we were there, sometime in the evening, the sea looked extremely beautiful. I saw the islands and hills in the distance, the birds in the air, and a few boys and girls playing on the beach. I also saw some fishermen coming out of the water with their catch. All this was indeed very interesting to look at. On the next day, my cousin and I collected some tree trunks from the forest near by. As my cousin’s house is close to the sea, we decided to make the raft on the beach itself.It took us almost the whole morning to make the raft. We then had our lunch and went to Banting, the nearest town, to buy fishing net. After that we returned to my cousin’s house. In the evening we put the raft on the sea. The water was still high, but the raft floated quite well. My cousin and I sat on it and began to row it by using the oars that we had made ourselves. We felt very happy indeed and continued to row it. We remained on it for a long time, but as it was already getting dark we did not go far.We returned to the shore and tied the raft to a tree. On the next day, we went out to catch some crabs and fish. We used the net that we had bought and caught a lot of fish. Then, we had our lunch and went out again on the raft. We continued to row it as far as we could. It was really a pleasure to be away from the shore. The sea was calm and we could row with ease. My cous in told me many interesting things about Morib. We then returned to the shore. In this way, I spent my holidays happily at Morib, a place I shall never forget.